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HomeThe PCMC Journalvol. 17 no. 1 (2021)

Infantile Inflammatory Bowel Disease

Maria Beatrice P. Teves

Discipline: medicine by specialism

 

Abstract:

Inflammatory bowel disease is a chronic disorder of the gastrointestinal tract that usually affects adolescents and young adults. It is rare among infants making up only less than 1% of pediatric cases. This is a case of infantile inflammatory bowel disease who presented with early onset hematochezia, with colonoscopy and histopathologic findings consistent with ulcerative colitis. He was managed with mesalazine, a 5-ASA derivative, the mainstay of treatment.



References:

  1. Kappelman, M. D., & Grand, R. J. (2008). Does Inflammatory Bowel Disease Develop in Infants? Inflammatory Bowel Diseases, 14(suppl_2), S6–S8.
  2. Moran, C. J., Klein, C., Muise, A. M., & Snapper, S. B. (2015). Very Early-Onset Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 21(5), 1166–1175. doi:10.1097/mib.0000000000000329
  3. Kliegman, R., Stanton, B., Schor, N. F., Behrman, R. E., & Nelson, W. E. (2020). Nelson Textbook of Pediatrics. Elsevier Incorporated.
  4. Shim, J. O. (2019). Recent Advances in Very Early-Onset Inflammatory Bowel Disease. Pediatric Gastroenterology, Hepatology & Nutrition, 22(1), 41. doi:10.5223/pghn.2019.22.1.41
  5. Ashton, J. J., Ennis, S., & Beattie, R. M. (2017). Early-Onset Paediatric Inflammatory Bowel Disease. Lancet Child Adolesc Health, 1(2), 147-158. doi:10.1016/S2352-4642(17)30017-2
  6. Moran, C. J., Klein, C., Muise, A. M., & Snapper, S. B. (2015). Very Early-Onset Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 21(5), 1166–1175. doi:10.1097/mib.0000000000000329
  7. Iacucci, M., de Silva, S., & Ghosh, S. (2010). Mesalazine in Inflammatory Bowel Disease: A Trendy Topic Once Again? Canadian Journal of Gastroenterology = Journal Canadien de Gastroenterologie, 24(2), 127-133. DOI: 10.1155/2010/586092
  8. Turner, D., Ruemmele, F. M., Orlanski-Meyer, E., et al. (2018). Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence-Based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr, 67(2), 257-291. doi:10.1097/MPG.0000000000002035
  9. Molodecky, N. A., & Kaplan, G. G. (2010). Environmental Risk Factors for Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y), 6(5), 339-346. PMID: 20567592; PMCID: PMC2886488